Functional analysis of a novel antagonistic antibody against the short epitope of the a1A-adrenergic receptor
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چکیده
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منابع مشابه
Functional analysis of a novel antagonistic antibody against the short epitope of the α1A-adrenergic receptor.
AIMS The alpha1A-adrenergic receptor (α1A-AR) regulates various vascular functions and participates in the pathogenesis of primary hypertension. However, highly specific and subtype-selective antagonists of α1A-AR have not been developed. METHODS AND RESULTS Two novel antibodies against the short peptides CP-7, which is located in the second extracellular loop of α1A-AR, and CPE-8, which is l...
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تاریخ انتشار 2012